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It might seem too daring to make changes to human subjects oversight programs by easing ethics review procedures. But several research organizations have found that some measured changes can help reduce investigators' regulatory burden without increasing risk to subjects.
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Research sites can improve the way they handle regulatory requirements and encourage more investigators to conduct research by making simple changes, an expert says.
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Review board mission creep: nearly every research organization experiences it, and most clinical trial sites resent it.
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An estimated 430,000 children worldwide became infected with HIV in 2008, mostly through birth or breastfeeding from an HIV-infected mother.
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AIDS-defining conditions and risks are different for HIV-positive patients who are older, usually defined as age 50 and above, experts say.
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Frailty is not a diagnosis that typically comes to mind when clinicians examine HIV patients, but with increasing numbers of older people being diagnosed or younger patients growing old with the disease, it should be on HIV clinicians' radar.
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On Jan. 29, 2009, the Food and Drug Administration (FDA) approved revisions to the lopinavir/ritonavir (Kaletra®) package insert to include drug-drug interaction information for concurrent lopinavir/ritonavir administration with inhaled medicines such as salmeterol or salmeterol in combination with fluticasone propionate (Serevent®, Advair®) and sildenafil (Revatio®).
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"We have a national responsibility to alleviate the HIV/AIDS-related suffering of African-Americans by ensuring that they have full knowledge ofand access toall proven forms of HIV prevention, treatment and care," Anthony S. Fauci, MD, director, National Institute of Allergy and Infectious Diseases said Feb. 7, 2010, commemorating the 10th annual National Black HIV/AIDS Awareness Day.
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Although the total number of annual perinatal HIV infections in the United States has decreased approximately 90% since 1991 and continue to fall in the most recent data set from 2004-2007 racial/ethnic disparities persist, the Centers for Disease Control and Prevention reports.